White Antibodies is one of the largest bulk manufacturers of Treponema pallidum antigen suspension for use in the manufacture of Syphilis testing.
The Reagent is well suited for use in TPHA & ELISA and other testing regimes using Microwell plate detection systems used in the Syphilis Testing Market.
About Treponema Pallidum
Treponema pallidum is the bacterium that causes syphilis, a sexually transmitted infection. Antigens derived from Treponema pallidum (Nichols strain) are useful in various scientific and clinical applications, primarily in the context of diagnosis and research. White Antibodies manufacture and supply T.pallidum antigens for a variety of uses:
- Diagnostic Testing: Treponema pallidum antigens are crucial for the serological diagnosis of syphilis. Tests such as the Treponema pallidum hemagglutination test (TPHA), and enzyme immunoassays (EIAs) use these antigens to detect antibodies produced in response to the infection.
- Research on Pathogenesis: Treponema pallidum antigens are used in studies to understand the pathogenesis of syphilis and its immunological responses. This research can lead to insights into how the bacterium evades the immune system and causes disease.
- Epidemiological Studies: Antigens are also used in epidemiological studies to assess the prevalence of syphilis in populations. These studies can help in monitoring the spread of the infection and the effectiveness of public health interventions.
- Differential Diagnosis: Treponema pallidum antigens can help differentiate syphilis from other treponemal infections, such as yaws or pinta, which are caused by other species of Treponema.
In Summary Treponema pallidum antigens play a critical role in the diagnosis, treatment, research, and understanding of syphilis and its impact on public health, please contact White Antibodies for further information.
Treponema pallidum antigen suspension
(Nichols Strain) directly from the current infection pool- If you need an antigen suspension to meet the high sensitivity and specificity demands required to meet the Gold standard in your Industry contact us today.
- Manufactured in state of the art facilities under strict regulation in the United Kingdom
- 30 years experience in Treponema pallidum suspension manufacture
- Material supplied at Standard 6×10 (8) or at a higher concentration of 1×10 (9) organisms per ml
- Free samples available for evaluation from current bulk batches
- All material supplied in Phospahte Buffered Saline and Azide at 0.1%
- COA supplied for each batch to confirm concentration and non viability of organism
Our Treponemes were originally sourced from leading GUM clinics in London in the 1970’s, whilst it is possible that the bug may have changed over time, it is our policy to replenish our seed stock to ensure we have the most current strains infecting the population. Several UK, USA and ASIAN treponema pallidum lines are held in our seed stocks, these are the current Nichols strain Treponema pallidum bugs infecting these continents.
We hold several cell lines of the Nichols strain of Treponema pallidum in secure offsite Liquid Nitrogen stores at two sites for use to seed production batches.
With over 30 years of experience refining production processes we have developed two key purity grades of antigen.
- TP 1 PLUS+ a cleaner harvest using refined processes suited for ELISA.
- TP 2 PLUS+ A superior antigen for use in TPHA manufacture containing background (ballast) cells of immune response which protects the treponemes during sonication during kit manufacture.
Improved Sensitivity & Specificity
Have a question? Wish to make an enquiry? Contact us and find out more, we’re happy to help if we can!